Genetic variation in AIDS viruses

Evidence for recent genetic variation in monkeypox viruses.

DNA from isolates of monkeypox virus, when digested with the endonuclease PstI, gave fragment-size profiles which correlated with the geographic area from which the isolate originated. Although some of the differences were located subterminally in the genome, others mapped to the central conserved region. Further differentiation of the viral genomes was sought by analysis of a short region with...

P-199: Genetic Variation Analysis of MIF in Endometriosis Patients

Background: Macrophage migration inhibitory factor (MIF) is a key pro-inflammatory cytokine that is secreted by active macrophages accumulated in ectopic tissue of endometriosis. It involves in pathophysiological events of endometriosis such as angiogenesis, cell proliferation and it can stimulate the synthesis of PGE2 that are necessary for survival and establishment of ectopic endometriosis t...

Genetic Variation of Choline Dehydrogenase Gene in Idiopathic Male Infertility

Infertility can be caused by an unexplained reduction in semen quality in males who present asnormal on physical examination and endocrine testing. There is some evidence that aberrantmetabolism of micronutrients such as choline may play a causative role in male factorinfertility. Choline is a crucial factor in the regulation of sperm membrane structure andmotility, and this nutrient plays an i...

Genetic Variation in MMP-1 Promoter Region and

Mitochondrial Genetic Variation in Iranian Infertile Men with Varicocele

Objective Several recent studies have shown that mitochondrial DNA mutations lead to major disabilities and premature death in carriers. More than 150 mutations in human mitochondrial DNA (mtDNA) genes have been associated with a wide spectrum of disorders. Varicocele, one of the causes of infertility in men wherein abnormal inflexion and distension of veins of the pampiniform plexus is observe...